Drug Standards
Apexbio Technology LLC Diclazuril 101831-37-2 10mM (in 1mL DMSO)
Diclazuril is a benzeneacetonitrile derivative displaying anticoccidial activity by targeting developmental stages of parasites It inhibits both asexual replication and sexual gametogenesis phases of coccidia thus disrupting the parasite s proliferative and reproductive cycle In pharmacological studies Diclazuril exhibits inhibitory efficacy against various species of Eimeria parasites associated with coccidial infections in vitro and in vivo with reported IC50 values typically ranging from 0 01 to 2 M depending on parasite strain and assay conditions Additionally this compound serves as an investigative tool in experimental models studying acute Toxoplasma gondii infection pathogenesis parasite-host interactions and therapeutic intervention strategies as well as research on protozoal mechanisms in equine protozoal myeloencephalitis (EPM)
Cayman Chemical ChlorambucIl-d8 1mg
An internal standard for the quantification of chlorambucil by GC- or LC-MS
Medchemexpress LLC Benzoic acid, 2-methoxy-5-methyl-, methyl ester | 63113-79-1 | MFCD06411343 | 1g
Ilurodoline impurity 10 is an impurity of Ilurodoline
Selleck Chemical LLC Xylazine HCl S2516-1g
Xylazine(BAY 1470 hydrochloride) is an 2-Adrenergic receptor agonist used as a sedative and muscle relaxant
Cayman Chemical RacecadotrIl 500mg
A prodrug form of thiorphan; reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats at 80 or 100 mg/kg, respectively; decreases duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea
Apexbio Technology LLC Fluconazole hydrate 155347-36-7 1g
Fluconazole hydrate (CAS 155347-36-7) is a small-molecule inhibitor targeting the fungal enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and arresting fungal growth Fluconazole hydrate exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies fluconazole hydrate demonstrates inhibitory activity with documented IC50 values typically ranging from 0 1 to 10 g/mL depending on fungal strain and experimental conditions Based on these pharmacological properties fluconazole hydrate holds research potential in antifungal pharmacology assays fungal infection model studies and evaluation of combinational antifungal therapies
Medchemexpress LLC Vonoprazan impurity 1 | 1807642-39-2 | 10mg
Vonoprazan impurity 1 is an impurity of Vonoprazan (HY-100007)
Sigma Aldrich Fine Chemicals Biosciences Moexipril Related Compound D United States Pharmacopeia (USP) Reference Standard | 1356019-89-0 | 20MG
Moexipril Related Compound D United States Pharmacopeia (USP) Reference Standard | Mol Wt: 541.08 | 1356019-89-0 | 20MG
Medchemexpress LLC Fostamatinib disodium hexahydrate | 914295-16-2 | 99.5% | 1 ML
Fostamatinib disodium hexahydrate is the oral proagent of the active compound R406, an orally available and competitive Syk/FLT3 inhibitor. R406 demonstrates potent inhibition of Syk and FLT3, with additional inhibitory effects on Lyn and Lck. This prodrug is highly bioavailable, rapidly absorbed, and fully converted to R406 in plasma, making it a valuable tool for research applications.
- Oral proagent of active compound R406
- Competitive Syk/FLT3 inhibitor (Ki of 30 nM, IC50 of 41 nM)
- Also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)
- Highly bioavailable and rapidly absorbed
- Completely converted to R406 in plasma
- Exhibits cytotoxicity against human Ramos cells (IC50 = 0.267 μM)
- For research use only
Medchemexpress LLC 15(S)-15-Methyl Prostaglandin F2α | 35700-23-3 | 99.8% | 25 MG
Carboprost is a metabolically stable synthetic analog of prostaglandin F2α. It stimulates uterine contractions and induces abortion, and is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester.
- Metabolically stable synthetic analog of prostaglandin F2α
- Stimulates uterine contractions
- Induces abortion
- Used for postpartum hemorrhage due to uterine atony
- Used for termination of pregnancy in the second trimester
![Medchemexpress LLC Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) | 37845-71-9 | 98.3% | 311.64 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403638-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) | 37845-71-9 | 98.3% | 311.64 | 50 MG
Clenbuterol impurity 1 (HY-33450) is a white to off-white solid with a molecular weight of 311.64 and a purity of 98.26% by HPLC. It is identified by CAS number 37845-71-9 and has the chemical name Ethanone, 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1).
- Purity of 98.26%
- White to off-white solid
- Molecular formula C12H17Cl3N2O
- Stable at room temperature for 3 years
- Stable in solvent for 2 years at -80°C
Apexbio Technology LLC Cefditoren Pivoxil 117467-28-4 10mM (in 1mL DMSO)
Cefditoren pivoxil is a small-molecule prodrug antibiotic targeting penicillin-binding proteins It is designed to inhibit these proteins thereby disrupting peptidoglycan cross-linking essential for bacterial cell wall integrity Cefditoren pivoxil exerts its biological activity primarily through inhibition of bacterial cell wall synthesis This mechanism confers bactericidal activity against a broad range of Gram-positive and Gram-negative organisms Based on these pharmacological properties cefditoren pivoxil holds research potential in studying bacterial susceptibility profiles characterizing resistance mechanisms in pathogens and evaluating pharmacokinetic-pharmacodynamic relationships associated with cephalosporins
Medchemexpress LLC Benazepril | 86541-75-5 | 99.9% | C24H28N2O5 | 25 MG
Benazepril is an orally active angiotensin-converting enzyme (ACE) inhibitor that reduces angiotensin-II production. It inhibits oxidative stress and apoptosis via the PI3K/Akt signaling pathway. This compound improves diabetic nephropathy and decreases proteinuria, making it suitable for studies of hypertension, heart failure, and diabetic nephropathy.
- Alleviates oxidative stress and inhibits cell apoptosis.
- Improves diabetic nephropathy in Wistar male rats.
- Decreases proteinuria, urea, creatinine, triglycerides, and total cholesterol levels.
- Increases albumin level, diminishes kidney volume, and ameliorates pathological changes.