Drug Standards
Selleck Chemical LLC Molidustat (BAY 85-3934) 5mg 1154028-82-6
Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD, respectively. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Netarsudil (AR-13324) 2HCl 2mg 1253952-02-1
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Siponimod (BAF312) 5mg 1230487-00-9
BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Encorafenib (LGX818) 5mg 1269440-17-6
Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Econazole nitrate 24169-02-6 5g
Econazole nitrate (24169-02-6) is a small-molecule inhibitor targeting the enzyme 14 -demethylase It is designed to disrupt ergosterol synthesis in fungal membrane sterol biosynthesis thereby decreasing membrane integrity altering permeability and attenuating fungal cellular growth Econazole nitrate exerts its biological activity primarily through inhibition of 14 -demethylase In vitro studies demonstrate antifungal activity with reported IC50 values against various fungal isolates typically ranging from approximately 0 05 to 1 g/mL depending on experimental parameters and organism specificity Based on these pharmacological properties econazole nitrate holds research potential in antifungal susceptibility testing exploration of drug resistance mechanisms in fungal strains characterization of dermatopathogenic microorganisms and drug target identification studies
Medchemexpress LLC Ticagrelor impurity 26 | 1644461-85-7 | 99.4% | C23H28F2N6O5S | 5 MG
Ticagrelor impurity 26 is an off-white to light yellow solid with a purity of 99.4%. This chemical is for research use only and intended for experienced personnel in appropriately equipped and authorized facilities. It is stable under recommended storage conditions, but incompatible with strong acids/alkalis, and strong oxidizing/reducing agents. Hazardous decomposition products may be emitted under fire conditions.
- Off-white to light yellow solid appearance
- Purity (LCMS) of 99.4%
- Stable under recommended storage conditions
- For research use only
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Selleck Chemical LLC Midostaurin (PKC412) 5mg 120685-11-2 CGP 41251
Midostaurin (pkc412, CGP 41251) is a multi-targeted kinase inhibitor, including PKC?/?/?, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFR? and VEGFR1/2 with IC50 ranging from 80-500 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical Salbutamol-d9 1mg
An internal standard for the quantification of salbutamol by GC- or LC-MS
Medchemexpress LLC N-acetyl mesalazine | 51-59-2 | 99.9% | C9H9NO4 | 5 MG
N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid and serves as a biomarker for evaluating its efficacy. It can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. This compound can be used in the study of diseases such as colitis and colon cancer.
- Primary intestinal metabolite of 5-aminosalicylic acid
- Serves as a biomarker for evaluating efficacy of 5-aminosalicylic acid
- Scavenges free radicals
- Reduces DNA base hydroxylation
- Ameliorates mucosal inflammation
- Can be used in the study of diseases such as colitis and colon cancer
- Inhibits OH radical-stimulated DNA base hydroxylation in calf thymus DNA
Medchemexpress LLC Donepezil-d5 hydrochloride | 1883548-90-0 | C24H25D5ClNO3 | 1 MG
Donepezil-d5 (hydrochloride) is a deuterium labeled version of Donepezil (Hydrochloride), which is a reversible and selective AChE inhibitor with an IC50 of 6.7 nM. It demonstrates high selectivity for AChE over BuChE and has shown neuroprotective effects against Aβ42 neurotoxicity. This product is for research use only and has not been fully validated for medical applications.
- Stable heavy isotopes used as tracers for quantitation
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- For research use only
Medchemexpress LLC Ticagrelor impurity 27 | 2096989-55-6 | 99.0% | C23H28F2N6O4S | 5 MG
Ticagrelor impurity 27 is an impurity of Ticagrelor (HY-10064).
- High purity (99.01%)
- Solid appearance
- Molecular weight of 522.57
- Store powder at -20°C for 3 years, 4°C for 2 years
- Store in solvent at -80°C for 6 months, -20°C for 1 month
- For research use only
Medchemexpress LLC Carboprost tromethamine | 58551-69-2 | 99.85% | C25H47NO8 | 50 MG
Carboprost tromethamine is a synthetic 15-methyl analogue of prostaglandin F2α. It effectively promotes uterine contraction and significantly reduces bleeding during and after delivery. It is for research use only.
- Solid appearance
- White to off-white color
- Shipped at room temperature in continental US; may vary elsewhere
- Sealed storage at 4°C, away from moisture (solid)
- In solvent storage: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
- Soluble in DMSO and H2O (100 mg/mL)
Medchemexpress LLC Lenalidomide | 191732-72-6 | C13H13N3O3 | 500 MG
Lenalidomide | 191732-72-6 | C13H13N3O3 | 500 MG